MORGANTOWN, W.Va. (AP) -- Joe Alexander scored 22 points to lead West Virginia to a 110-44 win over Maryland-Eastern Shore on Tuesday.

The Mountaineers (4-1) went on a 22-1 run to take a 46-13 lead with 2:52 left in the first half. Alexander showcased his entire arsenal, dunking twice -- once off an inbounds pass -- and hitting a jumper and an inside basket to score eight points during the run.

Alex Ruoff added 17 and John Flowers came off the bench to score 14 for West Virginia.

Denzel Jackson and Ed Tyson scored 10 apiece for Maryland-Eastern Shore (1-6), which has lost 33 of its last 38 games.

The Mountaineers led 52-18 at the half and took their largest lead on Flowers' free throw with 1:56 left that made it 106-36.

West Virginia had a 45-31 advantage in rebounding and scored 52 points in the paint. It also turned 27 Maryland-Eastern Shore turnovers into a season-best 44 points. West Virginia had 31 assists and tallied 10 blocks and 11 steals.

Maryland-Eastern Shore shot a season-worst 25.5 percent, missing 41 of 55 shots.