Fantasy baseball lineup advice for Friday: Can Clay Holmes shake off the rust?

Clay Holmes is set to make his second start for the Chicago Cubs on Friday, and if he can pitch more like he did before his injury, it should be a favorable matchup. AP Photo/Charlie Riedel

Check out all of our starting pitcher rankings and other lineup selection tools here to help you make smart fantasy baseball lineup decisions. All fantasy advice is geared toward ESPN 10-team leagues with standard scoring.

Note: All information is accurate as of the time of publication. For updates, as well as any breaking news that might impact today's MLB slate, be sure to check out the latest fantasy baseball buzz.


Other resources: RP depth chart | 2026 Rankings
ESPN's 2026 Player Rater | Betting notes for Friday


Pitchers to stream on Friday

  • Peter Lambert has yielded more than three runs just three times all season, the last coming June 29. Since then, he has posted a 2.29 ERA and 1.09 WHIP. Those ratios are impressive, but even more enlightening is that he fanned 43 over these 39 1/3 innings, as compared to 68 punchouts over his first 74 1/3 innings. It's his perceived lack of dominance that keeps Lambert's rostership below 50%, but the righty sets up to pad his total when the Houston Astros host the Seattle Mariners, whose lineup sports the ninth-highest strikeout rate facing righties.

  • Landen Roupp's season has been uneven. In 23 outings, he has 10 quality starts but has also surrendered at least four runs on eight occasions. The San Francisco Giants host the Colorado Rockies on Friday, which portends another quality effort from Roupp. The righty faces a lineup with the seventh-highest strikeout rate and 11th-lowest wOBA on the road against right-handers.

  • Clay Holmes is set to make his second start for the Chicago Cubs since coming off the IL after recovering from a broken fibula. He'll look to shake off the rust and pitch more like he did before getting hit in the leg when he takes the hill against the St. Louis Cardinals at Wrigley Field. It's a favorable matchup with the Cardinals struggling versus right-handed pitching, especially after dealing Lars Nootbaar at the trade deadline

  • After winning five straight decisions, Jake Bennett has lost two of his last three starts for the Boston Red Sox. He'll aim to get back on track in a road affair against the Pittsburgh Pirates. Bennett's control has been iffy lately, but the Pirates sport the seventh-lowest walk rate when facing left-handed pitching, along with the third-highest strikeout rate.

Hitters to stream on Friday