NFL Week 5 betting: Odds, lines and totals for every game

The NFL's two most recent MVPs will face off on "Monday Night Football" to close out Week 5. AP Photo/Gregory Bull

Week 5 gets underway with the Dallas Cowboys hosting the Tampa Bay Buccaneers on "Thursday Night Football." Laying 10 points, the Cowboys are the biggest favorite of the week.

The Cincinnati Bengals are the second-biggest favorite of the week. They visit the Miami Dolphins as 7-point road favorites.

Ten games have a spread of four points or lower. The Detroit Lions-Arizona Cardinals and Buffalo Bills-Los Angeles Rams matchups have the highest total of the week (53.5).

Here's a look at the odds for every game this week. The Kansas City Chiefs and Carolina Panthers are on a bye. (You can find our early bets for Week 5 here.)

Note: Odds by DraftKings and subject to change. All times Eastern.

Jump to:
TB-DAL | JAX-PHI | CIN-MIA | NYG-WSH
CLE-NYJ | CHI-GB | LV-NE | IND-PIT
HOU-TEN | MIN-NO | DEN-LAC | SF-SEA
DET-ARI | BAL-ATL | BUF-LAR


Tampa Bay Buccaneers vs. Dallas Cowboys -10
Thursday, 8:15 p.m., Prime Video


Line movement: Opened Cowboys -3.5

Moneyline: Buccaneers (+400); Cowboys (-535)
Total: 47.5; Opened: 52.5
FPI favorite: Cowboys by 11.4 with a 87% probability to win the game outright


Philadelphia Eagles vs. Jacksonville Jaguars -4.5
Sunday, 9:30 a.m., NFL Net


Line movement: Opened Eagles -2.5

Moneyline: Eagles (+180); Jaguars (-218)
Total: 43.5; Opened: 44.5
FPI favorite: Jaguars by 6.5 with a 73% probability to win the game outright


Chicago Bears -2.5 vs. Green Bay Packers
Sunday, 1 p.m., Fox


Line movement: Opened Packers -3

Moneyline: Bears (-148); Packers (+124)
Total: 44.5; Opened: 49.5
FPI favorite: Bears by 2.1 with a 58% probability to win the game outright


Check out the latest Super Bowl odds and major NFL awards futures.


Cincinnati Bengals -7 vs. Miami Dolphins
Sunday, 1 p.m., Fox


Moneyline: Bengals (-355); Dolphins (+280)
Total: 41.5; Opened: 48.5
FPI favorite: Bengals by 9.1 with a 81% probability to win the game outright


Indianapolis Colts vs. Pittsburgh Steelers -2.5
Sunday, 1 p.m., CBS


Moneyline: Colts (+110); Steelers (-130)
Total: 44.5; Opened: 47.5
FPI favorite: Colts by 0.2 with a 51% probability to win the game outright


New York Giants vs. Washington Commanders -3
Sunday, 1 p.m., Fox


Moneyline: Giants (+142); Commanders (-170)
Total: 43.5; Opened: 48.5
FPI favorite: Commanders by 3.4 with a 63% probability to win the game outright


Cleveland Browns vs. New York Jets -1.5
Sunday, 1 p.m., CBS


Moneyline: Browns (+110); Jets (-130)
Total: 40.5; Opened: 38.5
FPI favorite: Jets by 1.5 with a 56% probability to win the game outright


Las Vegas Raiders vs. New England Patriots -3.5
Sunday, 1 p.m., CBS


Line movement: Opened Patriots -8.5

Moneyline: Raiders (+164); Patriots (-198)
Total: 44.5; Opened: 44.5
FPI favorite: Patriots by 3.6 with a 64% probability to win the game outright


Houston Texans -6.5 vs. Tennessee Titans
Sunday, 1 p.m., CBS


Line movement: Opened Texans -3.5

Moneyline: Texans (-305); Titans (+245)
Total: 39.5; Opened: 43.5
FPI favorite: Texans by 4.3 with a 66% probability to win the game outright


Minnesota Vikings -1.5 vs. New Orleans Saints
Sunday, 1 p.m., Fox


Moneyline: Vikings (-125); Saints (+105)
Total: 42.5; Opened: 44.5
FPI favorite: Vikings by 0.8 with a 54% probability to win the game outright


Denver Broncos -3.5 vs. Los Angeles Chargers
Sunday, 4:05 p.m., CBS


Line movement: Opened Chargers -2.5

Moneyline: Broncos (-180); Chargers (+150)
Total: 42.5; Opened: 44.5
FPI favorite: Chargers by 0.1 with a 51% probability to win the game outright


San Francisco 49ers vs. Seattle Seahawks -2.5
Sunday, 4:25 p.m., Fox


Moneyline: 49ers (+124); Seahawks (-148)
Total: 47.5; Opened: 46.5
FPI favorite: 49ers by 1.4 with a 56% probability to win the game outright


Detroit Lions -4.5 vs. Arizona Cardinals
Sunday, 4:25 p.m., Fox


Line movement: Opened Lions -8.5

Moneyline: Lions (-218); Cardinals (+180)
Total: 53.5; Opened: 49.5
FPI favorite: Lions by 5.2 with a 69% probability to win the game outright


Baltimore Ravens -3.5 vs. Atlanta Falcons
Sunday, 8:20 p.m., NBC


Moneyline: Ravens (-205); Falcons (+170)
Total: 46.5; Opened: 48.5
FPI favorite: Ravens by 2.4 with a 58% probability to win the game outright


Buffalo Bills vs. Los Angeles Rams -2.5
Monday, 8:15 p.m., ESPN, ABC


Moneyline: Bills (+120); Rams (-142)
Total: 53.5; Opened: 53.5
FPI favorite: Rams by 2.4 with a 60% probability to win the game outright