Week 1 of the NFL season is officially underway.
The 2026 season kicked off Wednesday with the Seattle Seahawks taking down the New England Patriots 13-10 in a Super Bowl rematch, followed by a somewhat surprisingly easy win for the San Francisco 49ers over the Los Angeles Rams on Thursday in Australia.
The action continues with a 13-game Sunday slate, with the Buffalo Bills-Houston Texans matchup highlighting the early afternoon games. The Bills come in as slight favorites. The Sunday night game features a classic NFC East rivalry, as the Dallas Cowboys visit the New York Giants as 3-point road favorites.
A whopping 12 Week 1 games have spreads of 3.5 points or less. The Los Angeles Chargers are the biggest favorite of the week, laying 9.5 points to the Arizona Cardinals.
The week wraps up with Patrick Mahomes making his comeback from a torn ACL when the Kansas City Chiefs (-2.5, 43.5) host the Denver Broncos on "Monday Night Football" (8:15 ET on ABC/ESPN).
Here's a look at the odds for every Week 1 game.
Note: Odds by DraftKings
and subject to change.
Jump to:
NE-SEA | SF-LAR | TB-CIN | NO-DET
NYJ-TEN | BAL-IND | ATL-PIT | CHI-CAR
CLE-JAX | BUF-HOU | MIA-LV | GB-MIN
WSH-PHI | ARI-LAC | DAL-NYG | DEN-KC
Sunday
Tampa Bay Buccaneers at Cincinnati Bengals (-3.5)
1 p.m. ET on Fox, Paycor Stadium, Cincinnati
Moneyline: Bengals -198, Buccaneers +164
Total: 50.5 points
FPI favorite: Bengals by 3.2, 62.4% to win outright
New Orleans Saints at Detroit Lions (-7)
1 p.m. ET on Fox, Ford Field, Detroit
Moneyline: Lions -310, Saints +250
Total: 49.5 points
FPI favorite: Lions by 6.8, 73.6% to win outright
Check out each team's futures odds here. For the latest, visit DraftKings.
New York Jets at Tennessee Titans (-1.5)
1 p.m. ET on CBS, Nissan Stadium, Nashville, Tenn.
Moneyline: Titans -125, Jets +105
Total: 38.5 points
FPI favorite: Titans by 2.4, 58.0% to win outright
Baltimore Ravens (-3.5) at Indianapolis Colts
1 p.m. ET on CBS, Lucas Oil Stadium, Indianapolis
Moneyline: Ravens -175, Colts +145
Total: 47.5 points
FPI favorite: Ravens by 2.5, 59.5% to win outright
Atlanta Falcons at Pittsburgh Steelers (-5.5)
1 p.m. ET on Fox, Acrisure Stadium, Pittsburgh
Moneyline: Steelers -230, Falcons +190
Total: 41.5 points
FPI favorite: Steelers by 2.4, 58.0% to win outright
Chicago Bears (-3) at Carolina Panthers
1 p.m. ET on Fox, Bank of America Stadium, Charlotte, N.C.
Moneyline: Bears -170, Panthers +142
Total: 47.5 points
FPI favorite: Bears by 2.7, 58.2% to win outright
Cleveland Browns at Jacksonville Jaguars (-8.5)
1 p.m. ET on CBS, EverBank Stadium, Jacksonville, Fla.
Moneyline: Jaguars -455, Browns +350
Total: 39.5 points
FPI favorite: Jaguars by 7.9, 76.6% to win outright
Buffalo Bills (-1.5) at Houston Texans
1 p.m. ET on CBS, NRG Stadium, Houston
Moneyline: Bills -118, Texans -102
Total: 44.5 points
FPI favorite: Bills by 1.0, 53.7% to win outright
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Miami Dolphins at Las Vegas Raiders (-3)
4:25 p.m. ET on Fox, Allegiant Stadium, Las Vegas
Moneyline: Raiders -170, Dolphins +142
Total: 40.5 points
FPI favorite: Raiders by 3.0, 61.4% to win outright
Green Bay Packers at Minnesota Vikings (-1.5)
4:25 p.m. ET on CBS, U.S. Bank Stadium, Minneapolis
Moneyline: Vikings -122, Packers +102
Total: 46.5 points
FPI favorite: Packers by 1.8, 56.6% to win outright
Washington Commanders at Philadelphia Eagles (-6)
4:25 p.m. ET on Fox, Lincoln Financial Field, Philadelphia
Moneyline: Eagles -250, Commanders +205
Total: 44.5 points
FPI favorite: Eagles by 4.8, 66.3% to win outright
Arizona Cardinals at Los Angeles Chargers (-9.5)
4:25 p.m. ET on CBS, SoFi Stadium, Inglewood, Calif.
Moneyline: Chargers -500, Cardinals +380
Total: 47.5 points
FPI favorite: Chargers by 9.6, 80.2% to win outright
Dallas Cowboys (-3) at New York Giants
8:20 p.m. ET on NBC, MetLife Stadium, East Rutherford, N.J.
Moneyline: Cowboys -162, Giants +136
Total: 48.5 points
FPI favorite: Cowboys by 2.2, 58.3% to win outright
Monday
Denver Broncos at Kansas City Chiefs (-2.5)
8:15 p.m. ET on ESPN/ABC, GEHA Field at Arrowhead Stadium, Kansas City, Mo.
Moneyline: Chiefs -148, Broncos +124
Total: 43.5 points
FPI favorite: Chiefs by 2.5, 57.8% to win outright
Thursday's result
San Francisco 49ers vs. Los Angeles Rams (-3.5)
Melbourne Cricket Ground, Melbourne, Australia
Moneyline: Rams -198, 49ers +164
Total: 48.5 points
FPI favorite: Rams by 2.9, 60.3% to win outright
Wednesday's result
New England Patriots at Seattle Seahawks (-3.5)
Lumen Field, Seattle
Moneyline: Seahawks -180, Patriots +150
Total: 45.5 points
FPI favorite: Seahawks by 3.4, 61.1% to win outright