The Commanders take on the 49ers for a Monday night showdown. Can San Francisco go 6-0?
Here's what to know about the Week 6 matchup.
When is the game?
The game airs at 8:15 p.m. ET on ESPN.
How can fans watch?
Fans can catch all of the action in the ESPN App and in the NFL streaming hub.
New music for 'Monday Night Football'
ESPN and Apple Music will collaborate on music curation for "Monday Night Football" games throughout the 2026 NFL season.
Week 7: Dallas Cowboys at Philadelphia Eagles
Week 13: Cowboys at Seattle Seahawks
Week 15: New England Patriots at Chiefs