ESPN
    • NFL
    • NBA
    • MLB
    • NHL
    • Men's World Cup
    • WNBA
    • Golf
    • More Sports
    • Watch ESPN
      Watch
    • ESPN Fantasy
      Fantasy
    • Where to Watch
    • Search

    Cleveland Guardians @ Chicago White Sox

    CLE
    Cleveland GuardiansGuardiansCLE
    41-37, 22-20 Away
    CLE -114
    CHW
    Chicago White SoxWhite SoxCHW
    39-37, 24-12 Home
    • Gamecast
    • Preview
    • Odds
    • TicketsExternal Link

    Game Odds
    Odds by

    2026-06-22T23:40ZOpenMLTotalRL
    Cleveland GuardiansGuardiansCLE
    (41-37)
    (41-37, 22-20 Away)
    (41-37)
    Gavin Williams
    (9-4, 3.83)
    -115
    ML
    -114
    o7.5
    -118
    -1.5
    +144
    Chicago White SoxWhite SoxCHW
    (39-37)
    (39-37, 24-12 Away)
    (39-37)
    Anthony Kay
    (6-2, 4.61)
    u8
    -112
    -105
    u7.5
    -102
    +1.5
    -175
    See More Odds

    Recent Schedule

    DATEOPPRESULTSPREADTOTAL
    6/21@HOUL2-1+1.58.5
    6/20@HOUW8-1+1.58.5
    6/19@HOUL9-3+1.58.5
    6/18@MILW4-2+1.57.5
    6/17@MILL9-4+1.57.5

    Betting 101

    The Beginner's Guide to BettingReady to enter the world of sports betting? Here's everything you need to know to get started.

    Matchup Predictor

    Cleveland Guardians
    Chicago White Sox
    49.1
    %
    50.9
    %

    According to ESPN Analytics

    Brayan Rocchio
    CLE SS
    Sam Antonacci
    CHW LF
    Miguel Vargas
    CHW 3B
    Chase Meidroth
    CHW 2B
    Travis Bazzana
    CLE 2B
    Braden Montgomery
    CHW RF
    Gabriel Arias
    CLE SS
    David Fry
    CLE RF
    o0.5
    -248
    u0.5
    +183
    o0.5
    -209
    u0.5
    +156
    o0.5
    -212
    u0.5
    +157
    o0.5
    -167
    u0.5
    +125
    o0.5
    -168
    u0.5
    +126
    o0.5
    -163
    u0.5
    +123
    o0.5
    -161
    u0.5
    +121
    o0.5
    -156
    u0.5
    +118
    See More Odds
    Brayan Rocchio
    CLE SS
    Sam Antonacci
    CHW LF
    Chase Meidroth
    CHW 2B
    Travis Bazzana
    CLE 2B
    Braden Montgomery
    CHW RF
    Miguel Vargas
    CHW 3B
    Gabriel Arias
    CLE SS
    David Fry
    CLE RF
    o0.5
    -140
    u0.5
    +101
    o0.5
    -117
    u0.5
    -118
    o0.5
    -113
    u0.5
    -122
    o0.5
    +103
    u0.5
    -143
    o0.5
    +105
    u0.5
    -145
    o0.5
    +109
    u0.5
    -150
    o0.5
    +109
    u0.5
    -151
    o0.5
    +119
    u0.5
    -165
    See More Odds
    Gavin Williams
    CLE SP
    Anthony Kay
    CHW SP
    o5.5
    -152
    u5.5
    +119
    o4.5
    -152
    u4.5
    +119
    See More Odds
    Cleveland Guardians
    41-37
    Chicago White Sox
    39-37
    o3.5
    -140
    u3.5
    +110
    o3.5
    -120
    u3.5
    -110
    See More Odds

    Injury Report

    Cleveland Guardians
    Name, PosStatus
    Chase DeLauter
    RF
    10-Day IL
    Tanner Burns
    SP
    7-Day IL
    Carlos Hernandez
    RP
    60-Day IL
    Angel Martinez
    LF
    10-Day IL
    Jose Ramirez
    3B
    10-Day IL
    Chicago White Sox
    Name, PosStatus
    Kyle Teel
    C
    60-Day IL
    Everson Pereira
    RF
    7-Day IL
    Tyler Gilbert
    RP
    15-Day IL
    Prelander Berroa
    RP
    60-Day IL
    Noah Schultz
    SP
    15-Day IL
    Full Injury Report

    World Series

    TEAMODDS
    Los Angeles DodgersLADLAD
    +200
    New York YankeesNYYNYY
    +500
    Seattle MarinersSEASEA
    +800
    Atlanta BravesATLATL
    +900
    Milwaukee BrewersMILMIL
    +1200
    Philadelphia PhilliesPHIPHI
    +1300
    Tampa Bay RaysTBTB
    +2200
    Toronto Blue JaysTORTOR
    +2200
    TEAMODDS
    Texas RangersTEXTEX
    +2500
    Chicago CubsCHCCHC
    +2800
    Cleveland GuardiansCLECLE
    +3500
    Houston AstrosHOUHOU
    +4000
    San Diego PadresSDSD
    +6000
    Baltimore OriolesBALBAL
    +6500
    Pittsburgh PiratesPITPIT
    +7000
    AthleticsATHATH
    +7000
    See More MLB Futures
    Top Betting Headlines
    • Ex-Iona player ruled ineligible over point shaving
    • QB Sorsby officially drops lawsuit against NCAA
    • Cincinnati denies claim it knew of Sorsby's betting
    • U.S. Open bettors fade Scottie as odds lengthen
    • Sorsby to enter supplemental draft, ending saga
    • Big 12 sued Texas Tech hours before Sorsby's exit
    • Canes favored among crowded pack for '27 title
    • Deion on gambling scandal: 'Something's wrong'
    • Three teams ahead of Knicks in 2027 title odds
    • Oklahoma AG calls on Big 12 to suspend Sorsby
    ESPN
    • Terms of Use
    • Privacy Policy
    • Your US State Privacy Rights
    • Children's Online Privacy Policy
    • Interest-Based Ads
    • About Nielsen Measurement
    • Your Privacy Choices
    • Contact Us
    • Disney Ad Sales Site
    • Work for ESPN
    • Corrections
    GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Call 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in ONT. Eligibility restrictions apply. Terms: draftkings.com/sportsbook. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL.
    Copyright: © 2026 ESPN Enterprises, LLC. All rights reserved.