Buffalo Bills @ San Francisco 49ers
2-3, 1-2 Away
3
2-3, 1-2 Away
4-1, 2-0 Home
45
4-1, 2-0 Home
Game Leaders
126
R. FitzpatrickQB
16/26, 1 INT
126
303
A. SmithQB
18/24, 3 TD
303
35
B. SmithWR
1 CAR
35
106
F. GoreRB
14 CAR, 1 TD
106
40
S. ChandlerTE
4 REC
40
113
M. CrabtreeWR
6 REC, 1 TD
113
--
None
--
1
A. BrooksLB
1
6
G. WilsonSS
6 SOLO
6
7
P. WillisLB
7 SOLO
7
Team Stats
204
Total Yards
621
2
Turnovers
1
10
1st Downs
29
5-30
Penalties
7-53
2/10
3rd Down
7/11
0/0
4th Down
1/1
0/0
Red Zone
0/0
23:46
Possession
36:14
Game Information
San Francisco, CA
CBS
Referee:Jerome Boger
Team Stats
 | | |
|---|---|---|
| 1st Downs | 10 | 29 |
| Passing 1st downs | 6 | 11 |
| Rushing 1st downs | 4 | 18 |
| 1st downs from penalties | 0 | 0 |
| 3rd down efficiency | 2-10 | 7-11 |
| 4th down efficiency | 0-0 | 1-1 |
| Total Plays | 46 | 63 |
| Total Yards | 204 | 621 |
| Total Drives | 12 | 10 |
| Yards per Play | 4.4 | 9.9 |
| Passing | 115 | 310 |
| Comp/Att | 16/26 | 19/25 |
| Yards per pass | 4.3 | 12.4 |
| Interceptions thrown | 1 | 0 |
| Sacks-Yards Lost | 1-11 | 0-0 |
| Rushing | 89 | 311 |
| Rushing Attempts | 19 | 38 |
| Yards per rush | 4.7 | 8.2 |
| Red Zone (Made-Att) | 0-0 | 0-0 |
| Penalties | 5-30 | 7-53 |
| Turnovers | 2 | 1 |
| Fumbles lost | 1 | 1 |
| Interceptions thrown | 1 | 0 |
| Defensive / Special Teams TDs | 0 | 0 |
| Possession | 23:46 | 36:14 |
2025 Standings
American Football Conference
| AFC East | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| New England | 14 | 3 | 0 | .824 | 490 | 320 |
| Buffalo | 12 | 5 | 0 | .706 | 481 | 365 |
| Miami | 7 | 10 | 0 | .412 | 347 | 424 |
| New York | 3 | 14 | 0 | .176 | 300 | 503 |
National Football Conference
| NFC West | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Seattle | 14 | 3 | 0 | .824 | 483 | 292 |
| Los Angeles | 12 | 5 | 0 | .706 | 518 | 346 |
| San Francisco | 12 | 5 | 0 | .706 | 437 | 371 |
| Arizona | 3 | 14 | 0 | .176 | 355 | 488 |
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