The English sides secured dominant wins in Europe as Alessia Russo's hat trick inspired Arsenal to a 3-0 win over Benfica, while Chelsea secured a comfortable 2-0 victory against Roma.
Russo became the all-time leading English goalscorer in the Women's Champions League, breaking Fran Kirby's record with two cool strikes and a spot kick in a dominant home display.
Chelsea's unbeaten run continued as they cruised to victory courtesy of goals from Ellie Carpenter and Kadeisha Buchanan in the second half.
Relive the action from both games.
Arsenal secured back-to-back wins for the first time this season as they followed up their 2-1 comeback against Tottenham at the weekend.
The Gunners opened their European campaign with a laboured 1-0 win against HB Køge before surrendering a 2-0 lead against Paris FC to come away with just one point.
Sonia Bompastor's side are riding the crest of a wave after an unbeaten start to the season, and built on their momentum, digging deep to score twice against Roma.
Chelsea went top of the Women's Super League (WSL) this weekend after mounting a comeback against Crystal Palace to win 3-1 and leapfrog Manchester City courtesy of a superior goal difference.
Melvine Malard scored twice before winning a penalty, converted coolly by Sandy Baltimore whose impressive performance earned her a start against Roma tonight.
The Blues are yet to lose a game but have been less convincing in the Champions League and are working hard to strengthen their credentials as serious contenders for the trophy.